Literature Review Matrix of Articles Used in Critical Appraisal
Table 1
Literature Review Matrix of Articles Used in Critical Appraisal
| Study Citation and Level of Evidence | Purpose | Design | Sample | Measurement tool(s)/Instrument(s) | Statistical Analysis | Key Findings |
| Berkhof, F., Hertog, N., Uil, S., Kerstjens, H.,& Berg, J. (2013). Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease: A randomized control trial. Respiratory Research, 14 (125).
Level II |
Assess the effects of prophylactic azithromycin on cough-specific health statuses in COPD patients with chronic productive cough over the course of three months. | Single-center parallel group randomized double-blind placebo controlled trial | 84 adults > 40 years of age with COPD GOLD stage > 2 and chronic productive cough.
Azithromycin therapy group (n=42) and placebo group (n=42) |
Leicester Cough Questionnaire (LCQ)
St. George’s Respiratory Questionnaire (SGRQ) Short Form 36 (SF-36) Literature Review Matrix of Articles Used in Critical Appraisal
|
Intention-to-treat analysis.
Log-rank test. Kaplan-Meier curves. Chi-square tests. ANCOVA analysis. |
LCQ scores improved significantly in azithromycin group participants with low baseline scores 1.3 + 0.5 (95% CI 0.3; 2.3, p=0.001). Exacerbation frequency was reduced in azithromycin group. |
| Lee, H., Kim, S., Sok, S. (2016). Effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression of Korean older adults with mild cognitive impairment in care facilities. Journal of Nursing Scholarship 48 (3) 229-231.
Level III |
Examine effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression | Quasi-experimental pretest-postest control group | 48 adults > 65 years with mild cognitive impairment (MCI)
Intervention group (n=24); Control group (n=24) |
Serum homocysteine levels
Geriatric Depression Scale Short Form Korean Version (GDSSF-K) Mini Mental State Examination-Korean (MMSE-K)
|
Two group t test
Chi-square test for association Fisher’s exact test |
Intervention group had significantly increased cognitive function compared to control group (F=3.624, p=.021); significant decrease serum homocysteine level (F=6.974, p=.001) compared to control group; and significant alleviation of depression (F=10.849, p=.001) compared to control group |
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Table 1
Literature Review Matrix of Articles Used in Critical Appraisal
| Study Citation and Level of Evidence | Purpose | Design | Sample | Measurement tool(s)/Instrument(s) | Statistical Analysis | Key Findings |
| Berkhof, F., Hertog, N., Uil, S., Kerstjens, H.,& Berg, J. (2013). Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease: A randomized control trial. Respiratory Research, 14 (125).
Level II |
Assess the effects of prophylactic azithromycin on cough-specific health statuses in COPD patients with chronic productive cough over the course of three months. | Single-center parallel group randomized double-blind placebo controlled trial | 84 adults > 40 years of age with COPD GOLD stage > 2 and chronic productive cough.
Azithromycin therapy group (n=42) and placebo group (n=42) |
Leicester Cough Questionnaire (LCQ)
St. George’s Respiratory Questionnaire (SGRQ) Short Form 36 (SF-36)
|
Intention-to-treat analysis.
Log-rank test. Kaplan-Meier curves. Chi-square tests. ANCOVA analysis. |
LCQ scores improved significantly in azithromycin group participants with low baseline scores 1.3 + 0.5 (95% CI 0.3; 2.3, p=0.001). Exacerbation frequency was reduced in azithromycin group. |
| Lee, H., Kim, S., Sok, S. (2016). Effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression of Korean older adults with mild cognitive impairment in care facilities. Journal of Nursing Scholarship 48 (3) 229-231.
Level III |
Examine effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression | Quasi-experimental pretest-postest control group
Literature Review Matrix of Articles Used in Critical Appraisal |
48 adults > 65 years with mild cognitive impairment (MCI)
Intervention group (n=24); Control group (n=24) |
Serum homocysteine levels
Geriatric Depression Scale Short Form Korean Version (GDSSF-K) Mini Mental State Examination-Korean (MMSE-K)
|
Two group t test
Chi-square test for association Fisher’s exact test Literature Review Matrix of Articles Used in Critical Appraisal |
Intervention group had significantly increased cognitive function compared to control group (F=3.624, p=.021); significant decrease serum homocysteine level (F=6.974, p=.001) compared to control group; and significant alleviation of depression (F=10.849, p=.001) compared to control group |